Nevertheless, the use of intravenous iron in surgical patients, which is thought to bypass hepcidin‐mediated down‐regulation of ferroportin to stimulate erythropoiesis, has been seen to be effective to treat anaemia in a range of conditions and situations including in patients on ICU where baseline ferritin and TSAT are often very high [13]. The gene discussed is HAMP; the disease is anemia (phenotype).