In addition, other chronic underlying disease could also elevate CRP, such as cardiovascular disease, type 2 diabetes mellitus, age-related macular degeneration, hemorrhagic stroke, Alzheimer’s disease, Parkinson’s disease [24] this might alter the results of eCRPv and must therefore be examined in a further study, with a larger population. Here, CRP is linked to early-onset autosomal dominant Alzheimer disease.