EPAS1 and acute myeloid leukemia: To investigate the potential connection between Hif-2α and fatty acid β-oxidation, EtOH-treated AML-12 cells were treated with Hif-2α-siRNA (Fig. 2A), and the Hif-2α antagonist PT2399 (2.0 μM) [22, 23] (Fig. 2B, Additional file 1: Figure S2B).