METTL3 and colorectal cancer: For example, METTL3 stabilizes hexokinase 2 (HK2) and solute carrier family 2-facilitated glucose transporter member 1 (SLC2A1) (also known as glucose transporter, GLUT1) by mediating m6A modification in an insulin-like growth factor 2 mRNA-binding protein (IGF2BP)2/3-dependent manner to activate the glycolysis pathway, resulting in the tumorigenesis of colorectal cancer [16].