SP1 and pancreatic adenocarcinoma: As suggested in Figure 4 a and b, among the 16 target genes, only increased expression of 12 genes (YAP1, ERBB2, MST1R, YWHAZ, PDK1, CTNNB1, SP1, CIP2A, PIK3CA, PLAG1, MTPN, and MTDH) was positively linked to poor OS and RFS in PAAD.