Pallerla et al. (2017) find that conjugation of DOX with a peptidomimetic (Argaminonaphthylpropionic acid-Phe) that is highly specific for HER2-overexpressed cancer cell lines, has antiproliferative activity against HER2-positive cancer cells such as BT-474, SKBR-3 (human breast tumor cell lines), and Calu-3 (human lung cancer cell line). This evidence concerns the gene ERBB2 and cancer.