In ΔespZ infected FIS1-depleted cells, however, mitochondrial morphology more closely resembled mock-treated cells, and absence of LC3 recruitment; the Pearson correlation coefficient value for LC3/COXIV colocalization was lower in ΔespZ infection of FIS1-depleted cells compared to infected Scramble shRNA-transfected cells (Figure 7c). The gene discussed is COX4I1; the disease is infection.