AIFM1 and X-linked Charcot-Marie-Tooth disease type 4: AIFM1 mutation can contribute to several primary X-linked pathologies, two of which include: (i) combined oxidative phosphorylation deficiency 6 (COXPD6, MIM #300816) [244] and (ii) Cowchock syndrome (CMTX4, MIM #310490) [245].