TGFBR2 and Aortic dissection: Third, by downregulating the expression of circ_TGFBR2 in normal aortic VSMCs, the proliferation, migration, and phenotypic transition of VSMCs were promoted; by upregulating the expression of circ_TGFBR2 in VSMCs from aortic dissection patients, the proliferation, migration, and phenotypic transition of VSMCs were inhibited.