AND 2 of the following: - acute gastrointestinal symptoms (vomiting, diarrhea or abdominal pain) - rash or bilateral non-purulent conjunctivitis or both (oral, hands and feet signs) - echocardiographic signs of myocardial dysfunction, pericarditis, valvulitis or coronary abnormalities, or increased troponin/NT proBNP - evidence of coagulopathy (elevated D-dimer, impaired PT or PTT. Here, NPPB is linked to conjunctivitis.