Notably, quantification of IHC staining demonstrated that the level of GCN5L1 was positively correlated with the serum creatinine (Spearman r = 0.769, P = 0.003, n = 6) (Fig. 1H) and blood urea nitrogen (Spearman r = 0.594, P = 0.042, n = 6) (Fig. 1I) in AKI patients. This evidence concerns the gene BLOC1S1 and acute kidney injury.