New treatments also need to be considered, well-designed nano-antioxidants can scavenge reactive oxygen species in tumor-associated cells, presented as the downregulation of endothelial cells vascular endothelial growth factor in endothelial cells [46, 47], which was observed expanded after NACT in our study, thereby inhibiting angiogenesis and tumor growth. The gene discussed is VEGFA; the disease is neoplasm.