SHANK1 and autism: In addition, referring to the genes associated with autism shown in the SFARI (Simons Foundation Autism Research Initiative) gene database (https://gene.sfari.org/), ten genes were screened out encoding DEPs (ACTG1, GSTM1, SHANK1, GRIA2, PPP5C, MAPT, ClASP1, CLTC, ACHE, and SLC4A10) that were included in the 56 DEPs, which implies commonalities in the interplay between genetic and environmental factors.