Similarly, a small increase in atrophy was observed in the S-FTD (GR3) compared to GR1 (MAPT: cingulate, caudate, putamen; TARDBP: parietal and temporal lobe, anterior cingulate cortex) and GR2 patients (APOE ε4: superior parietal lobe and anterior cingulate cortex). Here, APOE is linked to frontotemporal dementia.