The correlation of the gene body hypermethylation with gene expression revealed CACNAH1 to be upregulated in ST08 treatment and CDH23 upregulation in ST09.CACNA1H is a voltage-gated calcium channel whose expression was found to correlate positively with a decrease in brain metastasis in the breast cancer PDX model [36], and mutations in CDH23 have been found in younger breast cancer patients [37]. The gene discussed is CDH23; the disease is breast carcinoma.