Comparing genome-wide DNA methylation with transcriptomics, we can co-relate ST09 mediated downregulation of oncogenes SCN5A, RPS6KA2 to promoter hypermethylation, and ST09 mediated upregulation of TSGs FAT3, PTPN11 to promoter hypomethylation FAT3 is a known tumor suppressor and is detected as a mutational cancer driver in Breast adenocarcinoma [75]. The gene discussed is RPS6KA2; the disease is breast adenocarcinoma.