The m7GMRRGs showed significantly higher RNA expression levels in melanoma when compared with normal tissues were DCP2, AGO2, LSM1, METTL1, SNUPN, CYFIP1, NUDT16, WDR4, DCPS, NUDT3, GEMIN5, LARP1, NCBP1, EIF4G3, NCBP2, IFIT5 (all P < 0.001). The gene discussed is WDR4; the disease is melanoma.