CHD6 and colorectal carcinoma: CHD6 KD in these CRC cells inhibited/decreased cell proliferation, colony formation, cell migration, invasion, sphere formation, patient-derived organoid (PDO)35 growth, G1-S progression, cell survival, oxygen consumption rate (OCR), ATP production, and mitochondrial mass (FACS analysis of Mitotracker Red staining) (Supplementary Figs. S2b–e, S3a–g).