Using four scRNA-Seq clusters defined by both normal and BCC cells as well as LY6D− and LY6D+ fractions (Normal: LY6DLow, Normal: LY6DHi, Tumor: LY6DLow, and Tumor: LY6DHi), we were able to impute and integrate these clusters onto the scATAC-Seq clustering for subsequent analysis (Fig. 3d). The gene discussed is LY6D; the disease is skin basal cell carcinoma.