Examining LY6D levels across all major cancers, we noted high levels in adenoid cystic carcinoma (ACC), bladder urothelial carcinoma (BLCA), cervical squamous cell carcinoma, and endocervical adenocarcinoma (CESC), esophageal carcinoma (ESCA), head and neck squamous cell carcinoma (HNSC), lung squamous cell carcinoma (LUSC), and pancreatic adenocarcinoma (PAAD) (Fig. 6a). Here, LY6D is linked to cancer.