NR3C1 and post-traumatic stress disorder: Besides modeling behavioral phenotypic traits resembling symptoms in PTSD patients, the animal model recapitulates deviations in the hypothalamic-pituitary-adrenal (HPA) axis response to stress (i.e., suppressed stress peak corticosterone levels [40]), which were previously linked to increased glucocorticoid receptor expression in the ventral subiculum of susceptible animals [40].