More specifically, exosome-delivered miR-15a accelerated the proliferation of clear cell renal cell carcinoma cells by targeting the BTG anti-proliferation factor 2 (BTG2)/Phosphatidylinositol 3-Kinase (PI3K)/AKT serine/Threonine Kinase (AKT) axis.21 Here, AKT1 is linked to clear cell renal carcinoma.