Supporting increased fibrosis, blinded meta-analysis of histological data in viral hepatitis (METAVIR) histopathological scoring of liver samples revealed a shift of 33% in Dpp4–/– mice to level 4 relative to littermate controls, while no Dpp4hep–/– mice were scored in this range (Figure 4N). The gene discussed is DPP4; the disease is viral hepatitis.