XIAP also induces proinflammatory signaling by involving receptor-interacting serine/threonine kinase 2 (RIPK2) and production of interleukin 8 (IL-8) which leads to neutrophil recruitment in cancer and during infection (Krieg et al. 2009; Andree et al. 2014; Daoud et al. 2022). This evidence concerns the gene CXCL8 and cancer.