We also do not know the effect of the mpv17 mutation in our casper zebrafish model, which could be relevant for obesity given that it is an inner mitochondrial membrane protein (D'Agati et al., 2017; Krauss et al., 2013; Spinazzola et al., 2006). The gene discussed is MPV17; the disease is obesity due to melanocortin 4 receptor deficiency.