Regarding of overall survival analysis, the Kaplan–Meier analysis indicated that HCC patients with both low expressions of YTHDF3 and PFKL had better survival time than those patients with both high expressions of YTHDF3 and PFKL (log-rank = 7.157, P = 0.0075) (Fig. 6h). Here, PFKL is linked to hepatocellular carcinoma.