PFKL and hepatocellular carcinoma: Kaplan–Meier analysis indicated that overexpression of PFKL was correlated with poor overall survival of HCC patients from Sun Yat-Sen Memorial Hospital (log-rank = 4.234, P = 0.039) (Supplementary Fig. 1c) and Sun Yat-Sen University Cancer Center (log-rank = 4.437, P = 0.0352) (Supplementary Fig. 1d).