Among them, a great mount of m6A “readers” such as YTHDC1/2, HNRNPA2B1, HNRNPC, HNRNPG, NKAP, IGF2BP1/2/3 and YTHDF1/2 are found to play significant roles in hepatocarcinogenesis and progression of HCC [12]. The gene discussed is IGF2BP1; the disease is hepatocellular carcinoma.