pcDNA3.1-SOCS5, SOCS5 siRNA, gga-miR-365-3p mimics or AG490 (a JAK/STAT pathway inhibitor) were transfected into CP-II cells infected with MG to further investigate the regulatory mechanism of gga-miR-365-3p on pMGA1.2. The gene discussed is SOCS5; the disease is myasthenia gravis.