More importantly, by treating the hepatoma cells with actinomycin D, we found that overexpression of CEBPA-DT reduced DDR2 mRNA degradation, and prolonged its half-life, thus increasing the DDR2 mRNA expression, meanwhile deletion of hnRNPC significantly inhibited this promotion, enhanced the DDR2 mRNA level (Fig. 6G). This evidence concerns the gene DDR2 and hepatocellular carcinoma.