Overexpression of cIAP1 (Myc-cIAP1) increased cell number and percentage of EdU positive cells of GBM#P3-, LN229- and U118MG-sh-TRIM56-S2 cells (Fig. 5d-e) which demonstrated that overexpression of cIAP1 restored the proliferative capacity of GBM cells with loss of TRIM56. This evidence concerns the gene BIRC2 and glioblastoma.