GNB1 and Harel-Yoon syndrome: Referring to the following databases: Berry DB, DECIPHER, OMIM, and DGV, 1p36.33 contains multiple functional genes such as SKI, GNB1, DVL1 and ATAD3A, among which ATAD3A gene is related to Harel-Yoon syndrome, and the possible clinical phenotypes include psychomotor retardation, mental retardation.