TGFβ is important for TEC pEMT, kidney fibrosis, and renal failure across kidney pathologies but TGFβ also has anti-inflammatory effects, which differs from IL11 that is pro-inflammatory (Supplementary Fig. 1)25,33–35 Thus, we were interested in comparing the effects of X203 versus anti-TGFβ (clone 1D11) in our model of AKI. The gene discussed is TGFB1; the disease is kidney failure.