As a hallmark of pathological remodeling in AAA, we observed the strongest interaction between TGFB1 with the TGFB1 receptor family and notably strong co-localization with MMP2 and MMP9, suggesting the role of TGFB1 pathway as one of the reminiscent factors that could link the presence of SNPs to the development of AAA. The gene discussed is MMP9; the disease is triple-A syndrome.