Similarly, higher interaction scores were found in endothelial cells, fibroblasts, and Macro/DCs in the dermis of DLE patients than in SLE patients and HCs, in which many receptors and ligands, such as CCR7, CCR2, CXCR3, and CCL19, were found to be highly expressed in DLE. Here, CCR7 is linked to systemic lupus erythematosus.