However, in iRBD, we see a few with the opposite effect; notably, the PD SCARB2 variant (PD beta = 0.06, p = 1.17e-09) is nominally associated with an earlier PD AAO (beta = −0.28, p = 0.028), but decreased risk for RBD (beta = −0.10, p = 0.045). Here, SCARB2 is linked to Parkinson disease.