The pattern of results for amyloid status attenuated with exclusion of those with dementia and MCI (n = 10, [-0.06, p=0.02] to [-0.03 p = 0.1]), but otherwise effect sizes remained similar after adjusting for APOE-ε4 and affective mental health problems at the time of cognitive assessment (A.5). This evidence concerns the gene APOE and dementia.