ENSG00000280371 and malaria: Some drug resistance phenotypes in malaria parasites involve mutations in multiple genes, and some species develop resistance to the same drug through mutations at different loci (for example, resistance to CQ is mediated through mutations in the chloroquine transporter gene, crt, and the multidrug resistance gene mdr1 in P. falciparum, but not in P. vivax or P. chabaudi[26].