PLAT and Stroke: Metabolic perturbations and inflammatory mediators playa fundamentalrole in both early and late adverse post-acute ischemic stroke outcomes.Using data from the observational MAGIC (MArker bioloGici nell’IctusCerebrale) study, we evaluated the effect of 130 serum metabolic features,using a nuclear magnetic spectroscopy approach, on the following outcomes:hemorrhagic transformation at 24 h after stroke, non-response to intravenousthrombolytic treatment with the recombinant tissue plasminogen activator(rt-PA), and the 3 month functional outcome.