Currently, several treatments for colitis are available, including nontargeted therapies such as 5-aminosalicylic acid (5-ASA), glucocorticoids, and immunosuppressants (azathioprine) (15), as well as targeted biologics, including anti-tumor necrosis factor (TNF) therapy and c-Jun N-terminal kinase (JNK) inhibitors (16). The gene discussed is TNF; the disease is colitis.