In addition, we observe by HPLC adenosine in CD73−/− mice at Day 4 indicating intracellular conversion of AMP to adenosine and subsequent transport of adenosine into the microenvironment by ENT1 transporters may have been mechanistically why CD73−/− mice were able to resolve caerulein‐induced pancreatitis by Day 7. The gene discussed is NT5E; the disease is pancreatitis.