NUPR1 and diabetic kidney disease: Electrophoretic mobility shift analysis revealed that NUPR1 could bind slightly to deoxyribonucleic acid (DNA), but this binding property can be augmented when phosphorylated by protein kinase A.9Previous reports have shown the abnormal expression of NUPR1 gene in various benign diseases including diabetic nephropathy, cardiomyocyte hypertrophy, and acute pancreatitis.10, 11, 12