It was suggested that molecular hydrogen treatment may mainly affect SAE through these pathways, including ABC transporters, 2‐oxocarboxylic acid metabolism, alanine, aspartate and glutamate metabolism, biosynthesis of amino acids, arginine biosynthesis, glycine, serine and threonine metabolism, phenylalanine, tyrosine and tryptophan biosynthesis, aminoacyl−tRNA biosynthesis, protein digestion and absorption, mineral absorption, and central carbon metabolism in cancer (Figure 7A,B). This evidence concerns the gene ABCG2 and cancer.