PDIA3 and obstructive sleep apnea syndrome: Additionally, in this study, we found that SLP1 expression was positively correlated with IL-6, FOS, FOSB, and JUN, whereas PDIA3 expression was negatively correlated with FOS, FOSB, and JUN. Although most of the 10 hub genes have not been studied in OSA, we speculate that these genes might be involved in the pathogenesis of OSA and its complications and form a regulatory network to coregulate OSA.