Various mutation forms and epimutations at FMR1 were identified to be the cause of a broad spectrum of clinical presentations, including FXS, autism, fragile X-associated ataxia (FXTAS), premature ovarian failure/insufficiency (FXPOI), attention-deficit disorder, learning disabilities, as well as psychologic, endocrine, autoimmune, and metabolic disorders (Hagerman et al., 2018). Here, FMR1 is linked to fragile X syndrome.