Such upregulation in prostate cancer promoted the proliferation and progression of cancer cells by activating PI3K/AKT/mTOR signaling (Yan et al., 2018), thereby being recognized as a biomarker in detecting prostate cancer and evaluating its aggressiveness (Varambally et al., 2008; Li et al., 2012). The gene discussed is MTOR; the disease is Familial prostate cancer.