To explore the potential therapeutic targets in PCa, we focused on those genes that strongly positively (r > 0.8 and p < 0.05) correlated with upregulated PNN, including FNBP4, TCERG1, RBM39, DDX39B and DMTF1. Ten possible pharmaceutical molecules were identified using the Enrichr package from the DsigDB database, based on their p-value. This evidence concerns the gene DDX39B and posterior cortical atrophy.