AGER and cancer: KEGG pathway enrichment analysis revealed that these hub pathways included “pathways in cancer” (hsa05200), “AGE-RAGE signaling pathway in diabetic complications” (hsa04933), “PI3K-AKT signaling pathway” (hsa04151), “Rap1 signaling pathway” (hsa04015), “HIF-1 signaling pathway” (hsa04066), and “endocrine resistance” (hsa01522).