GSEA showed that core enriched HSC/leukaemic stem cells (CE‐HSC/LSC) signature and various annotated HSC‐ or LSC‐relevant signatures were significantly enriched in patients with higher RUNX1 expression than their lower RUNX1 expression counter partners (Figure S7), suggesting its role in maintaining and promoting leukaemia growth. This evidence concerns the gene RUNX1 and leukemia.