DDIT3 and neoplasm: The difference between the results for wild‐type and mutated PARK2 in this study was seen in the response to placebo+R‐CHOP rather than ibrutinib+R‐CHOP, suggesting that in wild‐type PARK2, chemotherapy can induce apoptosis via the death pathway, whereas this response is inhibited in PARK2‐mutated tumours, making them more resistant to chemotherapy.