NFKB1 and atherosclerosis: Xie et al. found that Porphyromonas gingivalis could downregulate the expression of BAML1 and lead to rhythm disorders and recruit DNA methyltransferase 1 by activating the TLR-NF-κB signaling axis to promote the degradation of BMAL1 after methylation, activate the NF-κB signaling pathway to formulate a positive feedback loop, and increase oxidative stress, thereby stimulating atherosclerosis (Xie et al., 2020).