The results showed that high expression of TSLP, RASGRP1, APOD, and PTGER3 was correlated with cancer cell drug sensitivity to a variety of chemotherapeutic drugs, especially APOD, which was highly correlated with drug sensitivity to ARQ-680, SB-590885, PLX-4720, vemurafenib, and others. The gene discussed is PTGER3; the disease is cancer.