ASPS needs to be differentiated from many kinds of tumors in histopathology: (1) ASPSCR1-TFE3 translocation of renal cell carcinoma (RCC): this translocation is mostly balanced translocation and can also express TFE3, but it can constantly express renal cell carcinoma markers and CD10, so it is of clinical significance to pay close attention to renal masses. Here, TFE3 is linked to hereditary clear cell renal cell carcinoma.