As shown in Figure 9A, according to degree > 4.8, five components (isopongaflavone, gossypetin, myricetin, quercetin, and liquiritin) and four targets (AKR1B1, PTGS2, CA2, and ALOX5) were key and may play an important role in treating CKD. The gene discussed is ALOX5; the disease is chronic kidney disease.